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Ubiquitin Isopeptidase-IN-G5

CAS No. 108477-18-5

Ubiquitin Isopeptidase-IN-G5 ( NSC-144303;NSC 144303;NSC144303 )

产品货号. M10333 CAS No. 108477-18-5

A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥741 有现货
10MG ¥1270 有现货
25MG ¥2752 有现货
50MG ¥4869 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Ubiquitin Isopeptidase-IN-G5
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.
  • 产品描述
    A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases; induce a unique apoptotic pathway, which includes a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa, stabilization of the IAP antagonist Smac, but also the involvement of the death receptor pathway.
  • 同义词
    NSC-144303;NSC 144303;NSC144303
  • 通路
    Proteasome/Ubiquitin
  • 靶点
    DUB
  • 受体
    DUB
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    108477-18-5
  • 分子量
    414.39
  • 分子式
    C19H14N2O7S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: ≥ 31 mg/mL
  • SMILES
    O=C(/C(C1)=C/C2=CC=C([N+]([O-])=O)C=C2)/C(CS1(=O)=O)=C/C3=CC=C([N+]([O-])=O)C=C3
  • 化学全称
    4H-Thiopyran-4-one, tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-, 1,1-dioxide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Aleo E, et al. Cancer Res. 2006 Sep 15;66(18):9235-44.
产品手册
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